Julian C. Leslie, M.A., D.Phil., AFBPsS, C.Psychol, FPsSI.
Professor  of  Psychology, School of Psychology, University of Ulster, Coleraine, Northern Ireland, BT52 1SA, UK. 

 

Brief work description

I carry out research on behaviour pharmacology and animal models of psychiatric disorders.  Funding has been obtained in these areas, as well as for various applied projects.  I have worked on animal models of Alzheimer’s disease with Dr O’Hare (see publications) and am developing new research in this area with Dr Holscher and Dr Gault.

 

Selected publications from 2001:
Leslie, J. C. (2002).  Essential Behaviour Analysis.  London: Edward Arnold; New York: Oxford University Press,  pp. 228. ISBN 034076273X

Leslie, J.C. (2001). Selection in operant learning may fit a general model.  Behavioral and Brain Sciences, 24(2), 542.

Leslie, J.C. (2003). A history of reinforcement: the role of reinforcement schedules in behavior pharmacology. The Behavior Analyst Today, 4, 98-108.

Leslie JC, Shaw D, McCabe C.  How does extinction work? behavioral and pharmacological analysis of extinction of operant behavior in mice.  Paper presented at Association for Behavior Analysis Convention, San Francisco, Calif., May 2003. Abstract at:
http://www.abainternational.org/conv2003/program/events//66.htm

McCabe, C., Shaw, D., Atack, J.R., Street , L.J., Wafford , K.A., Dawson , G.R.,  Reynolds, D., & Leslie, J.C. (2004). Subtype-selective GABAergic drugs facilitate extinction of mouse operant behavior.  Neuropharmacology, 46 (2), 171-178.

Shaw, D., Dawson, G. R., Reynolds, D. S., McCabe, C., & Leslie, J.C. (2004). Effects of chlordiazepoxide on extinction and re-acquisition of operant behavior in mice.  Behavioural Pharmacology, 15(3), 225-232.

Leslie, J.C., Shaw, D., McCabe, C., Reynolds, D. S., & Dawson, G. R. (2004). Effects of drugs that potentiate GABA on extinction of positively-reinforced operant behaviour. Neuroscience and Biobehavioral Reviews, 28, 229-238.

McDaid, D.G., Kim, E.-M., Reid, R.E., Leslie, J.C., Cleary, J. & O'Hare, E. (2005)
Parenteral antioxidant treatment preserves temporal discrimination following
intrahippocampal aggregated Aβ(1-42) injections. Behavioural Pharmacology, 16(4), 237-242.

Leslie, J. C., Shaw, D., Gregg, G., McCormick, N., Reynolds, D. S., & Dawson, G. R. (2005). Effects of reinforcement schedule on facilitation of operant extinction by chlordiazepoxide.  Journal of the Experimental Analysis of Behavior, 84, 327-338.

Smyth, W.F., Leslie, J.C., McClean, S., Hannigan, B., McKenna, H.P., Doherty, B., Joyce, C., & O’Kane, E. (2006).  The characterisation of selected antidepressant drugs using electrospray ionisation with ion trap mass spectrometry and with quadropole time-of-flight  mass spectrometry and their determination by high-performance liquid chromatography/ electrospray ionisation tandem mass spectrometry. Rapid Communications in Mass Spectrometry, 20, 1637-1642.

Leslie, J. C.  (2006).  Herbert Spencer’s contributions to behavior analysis: A retrospective review of Principles of Psychology.  Journal of the Experimental Analysis of Behavior, 86, 123-129.

Grant income since 2001:

£2750  from Merck Neuroscience (for organising a scientific symposium)
£110,000 from Merck Neuroscience (for work on brain GABAergic systems in learning and extinction)
£161,000 from Wellcome Foundation (with E. Kim, and E. O’Hare for work on brain opioid mechanisms of feeding)
£28,200 from Northern Ireland Community Addiction Service (with B. Bunting for work on monitoring alcohol treatment outcomes)
£18,000 from Social Security Agency Northern Ireland (with C. Conliffe for a study of stress and absenteeism in agency staff)
£60,000 from EPSRC (with J. Shields and K. Boyce for the Human Behaviour in Fire Network)
£232,476 from BBSRC (for work on neural mechanisms of operant extinction)
£25,000 from Flax Trust (with B. Hannigan, F. Smyth, S. McClean, and H. McKenna for work on role of antidepressants in self-harm)