ART Web page information
Lecturer in Neurobiology
School of Psychology
University of Ulster,
Coleraine BT52 1SA, UK
Email; e.kim@ulster.ac.uk
Tel.: 0044-28- 70323321
1. Research Interests
The role of amyloidosis in Alzheimer’s disease, experimental modelling of Alzheimer’s disease-type behavioural deterioration, pharmacological interventions in Alzheimer’ disease.
Ongoing projects;
Reduction of neuroinflammation as a treatment strategy in Alzheimer’ disease; the utility of anti-oxidant compounds in the treatment of Alzheimer’ disease symptoms; effects of synaptic deterioration following neuronal exposure to Ab oligomers.
2. Research Funding
2005-2006. £12,150. Peptidergic Arrest of Oligomeric Amyloid Beta-Induced Deficits in Behavioural Performance. Senexis.
2001-2005. £161,000. Opioids, Reward and Feeding Behaviour. The Wellcome Trust.
3. Research Collaborations
Ongoing collaboration with Dr. Eugene O’Hare QUB, Professor David Spanswick, Warwick University School of Medicine, Dr David Scopes and Dr Mark Trehern Senexis Cambridge, Professor Shane O’Mara Institute of Neuroscience Trinity College Dublin, and Professor James Cleary University of Minnesota.
4. List of recent publications from 2001
Reid, R.E., Kim, E-M., Page, D. and O’Hare, E. (2007). Effects of thyroxine replacement on spatial learning and memory in an animal model of congenital hypothyroidism. Physiology and Behavior. 91: 299-303.
O’Hare, E., Kim, E-M., and Tierney, K.J. (2006). An operant determination of the behavioural mechanism of benzodiazepine enhancement of food intake. Psychopharmacology, 187(2): 138-142.
Richardson, R.L., Kim, E.-M., Gardiner, T. and O’Hare, E. (2005). Chronic intracerebroventricular infusion of lipopolysaccharide: Effects of ibuprofen treatment and behavioural and histopathological correlates. Behavioural Pharmacology, 16: 531-541.
McDaid, Kim, E.M., Reid, R.E., Leslie, J.C., Cleary, J. and O’Hare, E. (2005). Parenteral antioxidant treatment preserves temporal discrimination following intrahippocampal aggregated Ab(1-42 injections. Behavioural Pharmacology, 16: 237-242.
Eccles, S., Kim, E-M. and E. O’Hare, (2005). Granistron attenuates exercise-induced conditioned taste aversion in the rat. Appetite, 44: 325-328.
Kim, E.-M., Quinn, J.G., Levine, A.S. and O’Hare, E. (2004). A bi-directional m-opioid-opioid connection between the nucleus of the accumbens shell and the central nucleus of the amygdala in the rat. Brain Research, 1029(1): 135-139.
O’Hare, E., Shaw, D.L., Tierney, K.J., Kim, E-M. and Shephard, R.A. (2004) Behavioral and neurochemical mechanisms of action of mild stress in the enhancement of feeding. Behavioral Neuroscience 118: 173-177.
Quinn, J.G., O’Hare, E., Levine, A.S. and Kim, E-M. (2003). Evidence for a m-opioid-opioid connection between the paraventricular nucleus and ventral tegmental area in the rat. Brain Research, 991(1-2) 206-211.
Richardson, R.L., Kim, E-M., Shepherd, R.A., Gardiner T., Cleary, J. and O’Hare, E. (2002). Behavioural and histopathological analyses of ibuprofen treatment on the effect of aggregated Ab (1-42) injections in the CA3 area of the hippocampus in the rat. Brain Research, 954:1-10.
Kim, E-M., Grace, M.K., O’Hare E., Billington, C.J. and Levine, A.S. (2002). Injection of a-MSH, but not b-endorphin, into the PVN decreases POMC gene expression in the ARC. Neuroreport, 13(4): 497-500.
Kim, E-M., Shi, O., Olszewski, P., Grace, M.K., O’Hare, E., Billington, C.J. and Levine, A.S. (2001) Identification of central sites involved in butorphanol tartrate induced-feeding in rats. Brain Research, 907 (102): 125-129.